| Ident. | Authors (with country if any) | Title |
|---|
| 001239 (2015) |
Qi-Fei Zhong [République populaire de Chine] ; Rui Liu [République populaire de Chine] ; Gang Liu [République populaire de Chine] | Structure-activity relationship studies on quinoxalin-2(1H)-one derivatives containing thiazol-2-amine against hepatitis C virus leading to the discovery of BH6870. |
| 001272 (2015) |
Jun-Li Yang [Corée du Sud] ; Thi-Kim-Quy Ha ; Basanta Dhodary ; Euisun Pyo ; Ngoc Hieu Nguyen ; Hyomoon Cho ; Eunhee Kim ; Won Keun Oh | Oleanane triterpenes from the flowers of Camellia japonica inhibit porcine epidemic diarrhea virus (PEDV) replication. |
| 001335 (2015) |
Sheng Liu [République populaire de Chine] ; Wanxing Wei [République populaire de Chine] ; Yubin Li [République populaire de Chine] ; Xu Liu [République populaire de Chine] ; Xiaoji Cao [République populaire de Chine] ; Kechan Lei [République populaire de Chine] ; Min Zhou [République populaire de Chine] | Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents. |
| 001336 (2015) |
Hannah L. Peters [États-Unis] ; Dirk Jochmans [Belgique] ; Adriaan H. De Wilde [Pays-Bas] ; Clara C. Posthuma [Pays-Bas] ; Eric J. Snijder [Pays-Bas] ; Johan Neyts [Belgique] ; Katherine L. Seley-Radtke [États-Unis] | Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity. |
| 001344 (2015) |
Yi Wang [République populaire de Chine] ; Ying Sun [République populaire de Chine] ; Andong Wu [République populaire de Chine] ; Shan Xu [République populaire de Chine] ; Ruangang Pan [République populaire de Chine] ; Cong Zeng [République populaire de Chine] ; Xu Jin [République populaire de Chine] ; Xingyi Ge [République populaire de Chine] ; Zhengli Shi [République populaire de Chine] ; Tero Ahola [Finlande] ; Yu Chen [République populaire de Chine] ; Deyin Guo [République populaire de Chine] | Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis. |
| 001412 (2015) |
Jingjing Gao [République populaire de Chine] ; Xianjin Luo [République populaire de Chine] ; Yuhuan Li [République populaire de Chine] ; Rongmei Gao [République populaire de Chine] ; Haifeng Chen [République populaire de Chine] ; Dingjue Ji [République populaire de Chine] | Synthesis and Biological Evaluation of 2‐oxo‐pyrazine‐3‐carboxamide‐yl Nucleoside Analogues and Their Epimers as Inhibitors of Influenza A Viruses |
| 001557 (2014) |
Hao Chen [République populaire de Chine] ; Yun-Bao Ma [République populaire de Chine] ; Xiao-Yan Huang [République populaire de Chine] ; Chang-An Geng [République populaire de Chine] ; Yong Zhao [République populaire de Chine] ; Li-Jun Wang [République populaire de Chine] ; Rui-Hua Guo [République populaire de Chine] ; Wen-Juan Liang [République populaire de Chine] ; Xue-Mei Zhang [République populaire de Chine] ; Ji-Jun Chen [République populaire de Chine] | Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. |
| 001559 (2014) |
Diwakar Rai [République populaire de Chine] ; Wenmin Chen ; Peng Zhan ; Hong Liu ; Ye Tian ; Xin Liang ; Erik De Clercq ; Christophe Pannecouque ; Jan Balzarini ; Xinyong Liu | Synthesis and anti-HIV activity of 4-(naphthalen-1-yl)-1,2,5-thiadiazol-3-hydroxyl derivatives. |
| 001639 (2014) |
Javier Carbajo-Lozoya [Allemagne] ; Yue Ma-Lauer [Allemagne] ; Miroslav Maleševi [Allemagne] ; Martin Theuerkorn [Allemagne] ; Viktoria Kahlert [Allemagne] ; Erik Prell [Allemagne] ; Brigitte Von Brunn [Allemagne] ; Doreen Muth [Allemagne] ; Thomas F. Baumert [France] ; Christian Drosten [Allemagne] ; Gunter Fischer [Allemagne] ; Albrecht Von Brunn [Allemagne] | Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir |
| 001652 (2014) |
Adeyemi O. Adedeji [États-Unis] ; Kamalendra Singh [États-Unis] ; Ademola Kassim [États-Unis] ; Christopher M. Coleman [États-Unis] ; Ruth Elliott [États-Unis] ; Susan R. Weiss [États-Unis] ; Matthew B. Frieman [États-Unis] ; Stefan G. Sarafianos [États-Unis] | Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses. |
| 001661 (2014) |
Xiao Li [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Ye Tian [République populaire de Chine] ; Huiqing Liu [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Jan Balzarini [Belgique] ; Xinyong Liu [République populaire de Chine] | Discovery of novel diarylpyrimidines as potent HIV NNRTIs via a structure-guided core-refining approach. |
| 001662 (2014) |
Jun Wang [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Zhenyu Li [République populaire de Chine] ; Huiqing Liu [République populaire de Chine] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Xinyong Liu [République populaire de Chine] | Discovery of nitropyridine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors via a structure-based core refining approach. |
| 001700 (2014) |
Xiao Li [République populaire de Chine] ; Xueyi Lu [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Huiqing Liu [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Christophe Pannecouque [Belgique] ; Jan Balzarini [Belgique] ; Erik De Clercq [Belgique] ; Xinyong Liu [République populaire de Chine] | Arylazolyl(azinyl)thioacetanilides. Part 16: Structure-based bioisosterism design, synthesis and biological evaluation of novel pyrimidinylthioacetanilides as potent HIV-1 inhibitors. |
| 001783 (2014) |
Adriaan H. De Wilde [Pays-Bas] ; Dirk Jochmans [Belgique] ; Clara C. Posthuma [Pays-Bas] ; Jessika C. Zevenhoven-Dobbe [Pays-Bas] ; Stefan Van Nieuwkoop [Pays-Bas] ; Theo M. Bestebroer [Pays-Bas] ; Bernadette G. Van Den Hoogen [Pays-Bas] ; Johan Neyts [Belgique] ; Eric J. Snijder [Pays-Bas] | Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture |
| 001785 (2014) |
Julie Dyall [États-Unis] ; Christopher M. Coleman [États-Unis] ; Brit J. Hart [États-Unis] ; Thiagarajan Venkataraman [États-Unis] ; Michael R. Holbrook [États-Unis] ; Jason Kindrachuk [États-Unis] ; Reed F. Johnson [États-Unis] ; Gene G. Jr Olinger [États-Unis] ; Peter B. Jahrling [États-Unis] ; Monique Laidlaw [États-Unis] ; Lisa M. Johansen [États-Unis] ; Calli M. Lear-Rooney [États-Unis] ; Pamela J. Glass [États-Unis] ; Lisa E. Hensley [États-Unis] ; Matthew B. Frieman [États-Unis] | Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection |
| 001911 (2013) |
Darryl Falzarano ; Emmie De Wit ; Cynthia Martellaro ; Julie Callison ; Vincent J. Munster [États-Unis] ; Heinz Feldmann | Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin |
| 001970 (2013) |
Everett Clinton Smith [États-Unis] ; Hervé Blanc [France] ; Marco Vignuzzi [France] ; Mark R. Denison [États-Unis] | Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics |
| 001C46 (2012) |
Li-Jun Wang [République populaire de Chine] ; Chang-An Geng ; Yun-Bao Ma ; Xiao-Yan Huang ; Jie Luo ; Hao Chen ; Xue-Mei Zhang ; Ji-Jun Chen | Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents. |
| 001C47 (2012) |
Hye Ri Park [Corée du Sud] ; Hyunjun Yoon ; Mi Kyoung Kim ; Sung Dae Lee ; Youhoon Chong | Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV). |
| 001C54 (2012) |
Adeyemi O. Adedeji [États-Unis] ; Kamalendra Singh ; Nicholas E. Calcaterra ; Marta L. Dediego ; Luis Enjuanes ; Susan Weiss ; Stefan G. Sarafianos | Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase. |
| 001C74 (2012) |
Javier Carbajo-Lozoya [Allemagne] ; Marcel A. Müller ; Stephan Kallies ; Volker Thiel ; Christian Drosten ; Albrecht Von Brunn | Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506. |
